Small molecule targeting amyloid fibrils inhibits Streptococcus mutans biofilm formation

Abstract Amyloid fibrils are important scaffold in bacterial biofilms. Streptococcus mutans is an established cariogenic bacteria dwelling within biofilms, and C123 segment of P1 protein is known to form amyloid fibrils in S. mutans biofilms, among which C3 segment could serve as a promising anti-am...

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Autors principals:	Yuanyuan Chen, Guxin Cui, Yuqi Cui, Dongru Chen, Huancai Lin
Format:	Artigo
Idioma:	Inglês
Publicat:	SpringerOpen 2021-12-01
Col·lecció:	AMB Express
Matèries:	Amyloid fibrils Streptococcus mutans Biofilm formation Small molecule
Accés en línia:	https://doi.org/10.1186/s13568-021-01333-2
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