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Proteomics of Vitreous Humor Reveals PPARA, RXR, and LXR Are Possible Upstream Regulators of Proliferative Diabetic Retinopathy

Purpose: To investigate the key regulators of the disease by comparing the abundance of vitreous proteins between the patients with proliferative diabetic retinopathy (PDR) and the controls with idiopathic epiretinal membrane (iERM).Methods: Vitreous humor (VH) samples were derived from patients wit...

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Principais autores: Siyan Li, Enzhong Jin, Xuan Shi, Yi Cai, Hui Zhang, Mingwei Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-08-01
coleção:Frontiers in Medicine
Assuntos:
proliferative diabetic retinopathy
proteomics
vitreous humor
transcription factors
mass spectrometry
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmed.2021.724695/full
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