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Depletion of RBMS1 alleviates oxaliplatin chemoresistance in gastric cancer cells by suppressing the efflux function of ABCB1

Abstract Despite its declining overall incidence, gastric cancer (GC) remains a major global health challenge as the third leading cause of cancer-related mortality. In particular, the prognosis for advanced GC patients is quite unsatisfactory, largely due to the development of chemoresistance. Here...

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Principais autores: Changshun Yang, Yu Zhang, Yifan Chen, Song Tan, Yizhen Chen, Shaolin Liu, Xiaojun Lin, Shengtao Lin, Yulong Mi, Weihua Li
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-08-01
coleção:European Journal of Medical Research
Assuntos:
Gastric cancer
RBMS1
ABCB1
Chemoresistance
Oxaliplatin
Acesso em linha:https://doi.org/10.1186/s40001-026-05052-x
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