Narirutin mitigates neuroinflammation following traumatic brain injury and modulates microglial polarization via the JAK2/STAT3 signaling pathway

BackgroundTraumatic brain injury (TBI) causes irreversible cerebral damage characterized by neuroinflammation and neuronal injury, representing a critical factor contributing to poor prognosis in TBI patients. While existing studies have demonstrated Narirutin’s (Nar) neuroprotective effects in Park...

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Hauptverfasser:	Hebo Zhang, Junming Han, Chaolong Yan, Jiannan Mao, Huiying Yan, Wei Jin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-10-01
Schriftenreihe:	Frontiers in Neurology
Schlagworte:	Narirutin traumatic brain injury microglia neuroinflammation JAK2/STAT3 pathway
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1680790/full
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