SARS-CoV-2 spike-specific regulatory T cells (Treg) expand and develop memory in vaccine recipients suggesting a role for immune regulation in preventing severe symptoms in COVID-19

We enrolled healthy subjects that received 2 to 4 injections of mRNA-based vaccination to prevent COVID-19 months to a year from the last vaccine boost, and we found numerous SARS-CoV-2 spike-specific regulatory T cell (Treg) that developed T cell memory as effector memory T cells (TEM) and central...

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Principais autores:	Alessandra Franco, Jaeyoon Song, Christina Chambers, Alessandro Sette, Alba Grifoni
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis Group 2023-12-01
Series:	Autoimmunity
Assuntos:	regulatory t cells (treg) vaccine sars-cov-2 immune regulation t cell memory
Acceso en liña:	http://dx.doi.org/10.1080/08916934.2023.2259133
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