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Designing of multi-valent epitope vaccine displaying interactions with diverse HLA alleles against Candida auris using immuno-informatics

The emergence of multidrug resistance against several antifungal drugs and the absence of alternate therapy limits the treatment choices leading to the spread of Candida auris infections, especially in immunocompromised patients. This work aims to construct the multi-epitope vaccine using an immuno-...

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Principais autores: Vaishali Ahlawat, Kiran Sura, Mehak Dangi, Anil Kumar Chhillar
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-03-01
coleção:Journal of Genetic Engineering and Biotechnology
Assuntos:
Epitope
Immuno-informatics
Reverse vaccinology
Vaccine
Candida auris docking
Molecular dynamics simulation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1687157X25000186
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