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Loss of miR-451a enhances SPARC production during myogenesis.

MicroRNAs (miRNAs) are small noncoding RNAs that critically regulate gene expression. Their abundance and function have been linked to a range of physiologic and pathologic processes. In aged monkey muscle, miR-451a and miR-144-3p were far more abundant than in young monkey muscle. This observation...

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Hlavní autoři: Rachel Munk, Jennifer L Martindale, Xiaoling Yang, Jen-Hao Yang, Ioannis Grammatikakis, Clara Di Germanio, Sarah J Mitchell, Rafael de Cabo, Elin Lehrmann, Yongqing Zhang, Kevin G Becker, Vered Raz, Myriam Gorospe, Kotb Abdelmohsen, Amaresh C Panda
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2019-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0214301
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