The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention

The WNT pathway is one of the major signaling cascades frequently deregulated in human cancer. While research had initially focused on signal transduction centered on β-catenin as a key effector activating a pro-tumorigenic transcriptional response, nowadays it is known that WNT ligands can also ind...

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Principais autores:	Kerstin Menck, Saskia Heinrichs, Cornelia Baden, Annalen Bleckmann
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2021-01-01
叢編:	Cells
主題:	ROR1 ROR2 cancer WNT signaling non-canonical targeted therapy
在線閱讀:	https://www.mdpi.com/2073-4409/10/1/142
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