Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection.
Ym1 and RELMα are established effector molecules closely synonymous with Th2-type inflammation and associated pathology. Here, we show that whilst largely dependent on IL-4Rα signaling during a type 2 response, Ym1 and RELMα also have IL-4Rα-independent expression patterns in the lung. Notably, we f...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , |
|---|---|
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science (PLoS)
2018-11-01
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| سلاسل: | PLoS Pathogens |
| الوصول للمادة أونلاين: | https://doi.org/10.1371/journal.ppat.1007423 |
| الوسوم: |
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