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Epigenetic alteration and microRNA dysregulation in cancer

MicroRNAs (miRNAs) play pivotal roles in numerous biological processes, and their dysregulation is a common feature of human cancer. Thanks to recent advances in the analysis of the cancer epigenome, we now know that epigenetic alterations, including aberrant DNA methylation and histone modificatio...

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Principais autores: Hiromu eSuzuki, Reo eMaruyama, Eiichiro eYamamoto, Masahiro eKai
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013-12-01
Serier:Frontiers in Genetics
Fag:
microRNA
biomarker
tumor suppressor
histone modification
oncomiR
EZH2
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00258/full
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