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The impact of human brain geometry on the transport of an intrathecal tracer

Abstract Background Intrathecal contrast-enhanced magnetic resonance imaging (MRI), utilizing the contrast agent gadobutrol as cerebrospinal fluid (CSF) tracer is emerging as a useful method to study glymphatic function in the human brain. A consistent finding with this technique is large inter-indi...

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Principais autores: Andreas Solheim, Geir Ringstad, Per Kristian Eide, Lars Magnus Valnes, Kent-Andre Mardal
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2026-02-01
Series:Fluids and Barriers of the CNS
Assuntos:
Image registration
Idiopathic normal pressure hydrocephalus
Spontaneous intracranial hypotension
Idiopathic intracranial hypertension
Glymphatic function
Glymphatic MRI
Acceso en liña:https://doi.org/10.1186/s12987-026-00764-y
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