Plant-Produced Anti-Zika Virus Monoclonal Antibody Glycovariant Exhibits Abrogated Antibody-Dependent Enhancement of Infection

Monoclonal antibodies (mAb) against the envelope (E) protein of Zika virus (ZIKV) have shown great potential as therapeutics against the Zika epidemics. However, their use as a therapy may predispose treated individuals to severe infection by the related dengue virus (DENV) via antibody-dependent en...

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Detalhes bibliográficos

Principais autores:	Ming Yang, Haiyan Sun, Huafang Lai, Biswas Neupane, Fengwei Bai, Herta Steinkellner, Qiang Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-03-01
coleção:	Vaccines
Assuntos:	Zika virus monoclonal antibody (mAb) plant-made antibody antibody dependent enhancement of infection (ADE) antibody-dependent cellular cytotoxicity (ADCC) Fc effector function
Acesso em linha:	https://www.mdpi.com/2076-393X/11/4/755
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