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Techniques for transferring host-pathogen protein interactions knowledge to new tasks

We consider the problem of building a model to predict protein-protein interactions (PPIs) between the bacterial species Salmonella Typhimurium and the plant host Arabidopsis thaliana which is a host-pathogen pair for which no known PPIs are available. To achieve this, we present approaches, which u...

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Kaydedildi:
Asıl Yazarlar: Meghana eKshirsagar, Sylvia eSchleker, Jaime eCarbonell, Judith eKlein-Seetharaman
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015-02-01
Seri Bilgileri:Frontiers in Microbiology
Konular:
Transfer Learning
protein interaction prediction
host pathogen protein interactions
plant pathogen protein interactions
machine learning methods
Kernel mean matching
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00036/full
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