Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer

Abstract Uveal melanoma (UM) is the most common intraocular cancer in adults, with metastatic disease (mUM) occurring in approximately half of the patients. Tebentafusp, an immune-mobilizing monoclonal T cell receptor against cancer (ImmTAC), is a therapeutic shown to improve overall survival (OS) i...

Ful tanımlama

Kaydedildi:

Detaylı Bibliyografya
Asıl Yazarlar:	Esra Güç, Agatha Treveil, Emma Leach, Anna Broomfield, Antonio Camera, James Clubley, Paula Nieto Garcia, Anastasiya Kazachenka, Rahul Khanolkar, Luis del Carpio, Holger Heyn, Jessica C. Hassel, Joseph J. Sacco, Sarah Stanhope, Laura Collins, Josep M. Piulats, Koustubh Ranade, Adel Benlahrech
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Nature Portfolio 2025-03-01
Seri Bilgileri:	Nature Communications
Online Erişim:	https://doi.org/10.1038/s41467-025-57470-w
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer

Benzer Materyaller