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Salvianolic acid A, a novel matrix metalloproteinase-9 inhibitor, prevents cardiac remodeling in spontaneously hypertensive rats.

Cardiac fibrosis is a deleterious consequence of hypertension which may further advance to heart failure and increased matrix metalloproteinase-9 (MMP-9) contributes to the underlying mechanism. Therefore, new therapeutic strategies to attenuate the effects of MMP-9 are urgently needed. In the prese...

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Bibliografiske detaljer
Principais autores: Baohong Jiang, Defang Li, Yanping Deng, Fukang Teng, Jing Chen, Song Xue, Xiangqian Kong, Cheng Luo, Xu Shen, Hualiang Jiang, Feng Xu, Wengang Yang, Jun Yin, Yanhui Wang, Hui Chen, Wanying Wu, Xuan Liu, De-an Guo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3606118?pdf=render
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