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The Proteome of Neuromelanin Granules in Dementia with Lewy Bodies

Neuromelanin granules (NMGs) are organelle-like structures present in the human <i>substantia nigra pars compacta</i>. In addition to neuromelanin, NMGs contain proteins, lipids and metals. As NMG-containing dopaminergic neurons are preferentially lost in Parkinson’s disease and dementia with Lewy b...

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Principais autores: Maximilian Wulf, Katalin Barkovits, Karin Schork, Martin Eisenacher, Peter Riederer, Manfred Gerlach, Britta Eggers, Katrin Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-11-01
coleção:Cells
Assuntos:
neuromelanin granules
<i>substantia nigra pars compacta</i>
neurodegeneration
dementia with Lewy bodies
proteomics
stress granules
Acesso em linha:https://www.mdpi.com/2073-4409/11/22/3538
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