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Reduced NK cell frequency in older patients with evolving fractures is linked to a distinct inflammatory cytokine profile

Abstract Background Proximal hip fractures represent a profound acute physiological stress in older adults and are often followed by infections, delayed recovery, and functional decline. These complications occur more frequently in frail individuals with reduced physiological resilience and impaired...

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Principais autores: Julia P. Moch, Jolane Kappes, Rodrigo Gutierrez Jauregui, Hagen Schmaus, Malou-Sophie Dietrich, Daniel A. Thies, Lennart M. Roesner, Thomas Werfel, Reinhold Förster, Dorothee von Witzendorff, Jennifer Debarry, Marcel Winkelmann, Swantje Oberthür, Jan-Dierk Clausen, Manfred Gogol, Markus Cornberg, Anke R. M. Kraft, Christian Niehaus
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-07-01
Serier:Immunity & Ageing
Fag:
Age-associated immune dysfunction
Fractures
Frailty
NK cells
Soluble immune mediators
Online adgang:https://doi.org/10.1186/s12979-026-00585-5
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