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Human beta-defensin 3 is up-regulated in cutaneous leprosy type 1 reactions.

<h4>Background</h4>Leprosy, a chronic granulomatous disease affecting the skin and nerves, is caused by Mycobacterium leprae (M. leprae). The type of leprosy developed depends upon the host immune response. Type 1 reactions (T1Rs), that complicate borderline and lepromatous leprosy, are due to an in...

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Autori principali: Anna L Cogen, Stephen L Walker, Chrissy H Roberts, Deanna A Hagge, Kapil D Neupane, Saraswoti Khadge, Diana N J Lockwood
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS Neglected Tropical Diseases
Accesso online:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001869&type=printable
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