Triazole Derivatives Target 14α–Demethylase (LDM) Enzyme in <i>Candida albicans</i> Causing Ergosterol Biosynthesis Inhibition

<i>Candida albicans</i> is the most dominant and prevalent cause of fungal infections in humans. Azoles are considered as first-line drugs for the treatment of these infections. However, their prolonged and insistent use has led to multidrug resistance and treatment failures. To overcome this, modif...

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Bibliografische gegevens

Hoofdauteurs:	Irfan A. Rather, Jamal S. M. Sabir, Amer H. Asseri, Mohmmad Younus Wani, Aijaz Ahmad
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2022-06-01
Reeks:	Journal of Fungi
Onderwerpen:	triazole derivatives <i>C. albicans</i> ergosterol molecular docking simulation
Online toegang:	https://www.mdpi.com/2309-608X/8/7/688
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