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Pharmacokinetics of Venetoclax Co-Administered with Posaconazole in Patients with Acute Myeloid Leukemia

The Food and Drug Administration currently approves the combination of hypomethylating agents (HMA), azacytidine or decitabine with venetoclax (VEN) for acute myeloid leukemia (AML) patients aged more than 75 years and for patients unsuitable for intensive chemotherapy. The risk of fungal infection...

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Principais autores: Simona De Gregori, Eleonora Gelli, Mara Capone, Giulia Gambini, Elisa Roncoroni, Marianna Rossi, Claudia Patricia Tobar Cabrera, Gianluca Martini, Ludovica Calabretta, Luca Arcaini, Riccardo Albertini, Patrizia Zappasodi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-06-01
Serier:Pharmaceutics
Fag:
acute myeloid leukemia
elderly patients
venetoclax
posaconazole
HPLC-MS/MS
dose adjustment
Online adgang:https://www.mdpi.com/1999-4923/15/6/1680
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