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Long-term maintenance of diphtheria-specific antibodies after booster vaccination is hampered by latent infection with Cytomegalovirus

Abstract Many currently used vaccines are less immunogenic in the elderly compared to young adults. The impact of latent infection with Cytomegalovirus (CMV) on vaccine-induced antibody responses has been discussed controversially. We have demonstrated that recall responses to diphtheria vaccination...

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Detalhes bibliográficos
Principais autores: Birgit Weinberger, Michael Keller, Beatrix Grubeck-Loebenstein
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-06-01
coleção:Immunity & Ageing
Assuntos:
Acesso em linha:http://link.springer.com/article/10.1186/s12979-017-0099-y
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