CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells
CRISPR-Cas9 generates double-strand breaks, which pose a threat to genome integrity. Here the authors show loss of heterozygosity in edited hematopoietic progenitor cells.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2021-08-01
|
| Colección: | Nature Communications |
| Acceso en línea: | https://doi.org/10.1038/s41467-021-25190-6 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
