Regulators of homologous recombination deficiency identified by machine learning using somatic multi-omics data

Using somatic multi-omics data and explainable artificial intelligence, this study identifies novel alterations underlying homologous recombination repair deficiency across cancers. Homologous recombination deficiency (HRD) is a critical biomarker for guiding targeted therapies, yet the full range o...

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Autors principals:	Renan Valieris, Lucas Rosa, Luan Martins, Alexandre Defelicibus, Dirce Maria Carraro, Diana Noronha Nunes, Emmanuel Dias-Neto, Rafael Rosales, Israel Tojal da Silva
Format:	Artigo
Idioma:	Inglês
Publicat:	Life Science Alliance LLC 2026-02-01
Col·lecció:	Life Science Alliance
Accés en línia:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503531
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