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The role of hexokinases in epigenetic regulation: altered hexokinase expression and chromatin stability in yeast

Abstract Background Human hexokinase 2 (HK2) plays an important role in regulating Warburg effect, which metabolizes glucose to lactate acid even in the presence of ample oxygen and provides intermediate metabolites to support cancer cell proliferation and tumor growth. HK2 overexpression has been o...

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Principais autores: Srinivasu Karri, Quinn Dickinson, Jing Jia, Yi Yang, Haiyun Gan, Zhiquan Wang, Yibin Deng, Chuanhe Yu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-08-01
coleção:Epigenetics & Chromatin
Assuntos:
Hexokinase
2-deoxy-D-glucose
Histone chaperones
eSPAN
Chromatin replication
Yeast
Acesso em linha:https://doi.org/10.1186/s13072-024-00551-9
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