Tissue clearing and immunostaining to visualize the spatial organization of vasculature and tumor cells in mouse liver

The liver has a complex and hierarchical segmental organization of arteries, portal veins, hepatic veins and lymphatic vessels. In-depth imaging of liver vasculature and malignancies could improve knowledge on tumor micro-environment, local tumor growth, invasion, as well as metastasis. Non-invasive...

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Auteurs principaux:	Nicola Frenkel, Susanna Poghosyan, Jan Willem van Wijnbergen, Lotte van den Bent, Liza Wijler, André Verheem, Inne Borel Rinkes, Onno Kranenburg, Jeroen Hagendoorn
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-03-01
Collection:	Frontiers in Oncology
Sujets:	tissue clearing liver vasculature CLARITY 3DISCO iDISCO tumor micro environment
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1062926/full
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