Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus.
At the imprinted Rasgrf1 locus in mouse, a cis-acting sequence controls DNA methylation at a differentially methylated domain (DMD). While characterizing epigenetic marks over the DMD, we observed that DNA and H3K27 trimethylation are mutually exclusive, with DNA and H3K27 methylation limited to the...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2008-08-01
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| Col·lecció: | PLoS Genetics |
| Accés en línia: | http://europepmc.org/articles/PMC2475503?pdf=render |
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