CD40L/IL-4–stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM

Abstract: CD40L/interleukin-4 (IL-4) stimulation occurs in vivo in the tumor microenvironment and induces global translation to varying degrees in individuals with chronic lymphocytic leukemia (CLL) in vitro. However, the implications of CD40L/IL-4 for the translation of specific genes is not known....

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Autori principali:	Larissa Lezina, Ruth V. Spriggs, Daniel Beck, Carolyn Jones, Kate M. Dudek, Aleksandra Bzura, George D.D. Jones, Graham Packham, Anne E. Willis, Simon D. Wagner
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2018-08-01
Serie:	Blood Advances
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2473952920309046
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