Evidence for presence and functional effects of Kv1.1 channels in β-cells: general survey and results from mceph/mceph mice.

BACKGROUND:Voltage-dependent K(+) channels (Kv) mediate repolarisation of β-cell action potentials, and thereby abrogate insulin secretion. The role of the Kv1.1 K(+) channel in this process is however unclear. We tested for presence of Kv1.1 in different species and tested for a functional role of...

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Detalhes bibliográficos

Principais autores:	Zuheng Ma, Catharina Lavebratt, Malin Almgren, Neil Portwood, Lars E Forsberg, Robert Bränström, Erik Berglund, Sture Falkmer, Frank Sundler, Nils Wierup, Anneli Björklund
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2011-04-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3071710?pdf=render
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