Novel Multi-Antigen Orf-Virus-Derived Vaccine Elicits Protective Anti-SARS-CoV-2 Response in Monovalent and Bivalent Formats

Prime-2-CoV_Beta is a novel Orf virus (ORFV)-based COVID-19 vaccine candidate expressing both the nucleocapsid and spike proteins of SARS-CoV-2 with the receptor-binding domain (RBD) of the Beta strain. This candidate was shown to be safe and immunogenic in a first-in-human Phase I clinical trial. W...

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Principais autores:	Dominique Julien Burri, Louis Renz, Melanie Mueller, Felix Pagallies, Ute Klinkhardt, Ralf Amann, Madiha Derouazi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-05-01
Colecção:	Vaccines
Assuntos:	Orf virus COVID-19 vaccine parapoxvirus
Acesso em linha:	https://www.mdpi.com/2076-393X/12/5/490
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