Utilizing systems biology to reveal cellular responses to peroxisome proliferator-activated receptor γ ligand exposure
Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that, upon activation by ligands, heterodimerizes with retinoid X receptor (RXR), binds to PPAR response elements (PPREs), and activates transcription of downstream genes. As PPARγ plays a central role in adipogenesis, fatty...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2021-01-01
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| Serier: | Current Research in Toxicology |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2666027X21000165 |
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