Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells.
A 30-node signed and directed network responsible for self-renewal and pluripotency of mouse embryonic stem cells (mESCs) was extracted from several ChIP-Seq and knockdown followed by expression prior studies. The underlying regulatory logic among network components was then learned using the initia...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2014-08-01
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| Schriftenreihe: | PLoS Computational Biology |
| Online-Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25122140/pdf/?tool=EBI |
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