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Implementation and use of whole exome sequencing for metastatic solid cancer

Background: Genomically-guided clinical trials are performed across different tumor types sharing genetic mutations, but trial organization remains complex. Here we address the feasibility and utility of routine somatic and constitutional exome analysis in metastatic cancer patients. Methods: Exoma...

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Hlavní autoři: Manon Réda, Corentin Richard, Aurelie Bertaut, Julie Niogret, Thomas Collot, Jean David Fumet, Julie Blanc, Caroline Truntzer, Isabelle Desmoulins, Sylvain Ladoire, Audrey Hennequin, Laure Favier, Leila Bengrine, Julie Vincent, Alice Hervieu, Jean-Florian Guion Dusserre, Come Lepage, Pascal Foucher, Christophe Borg, Juliette Albuisson, Laurent Arnould, Sophie Nambot, Laurence Faivre, Romain Boidot, Francois Ghiringhelli
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020-01-01
Edice:EBioMedicine
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2352396419308394
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