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LpxK Is Essential for Growth of <named-content content-type="genus-species">Acinetobacter baumannii</named-content> ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

ABSTRACT Acinetobacter baumannii ATCC 19606 can grow without lipid A, the major component of lipooligosaccharide. However, we previously reported that depletion of LpxH (the fourth enzyme in the lipid A biosynthetic pathway) prevented growth of this strain due to toxic accumulation of lipid A pathwa...

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Principais autores: Jun-Rong Wei, Daryl L. Richie, Mina Mostafavi, Louis E. Metzger, Christopher M. Rath, William S. Sawyer, Kenneth T. Takeoka, Charles R. Dean
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017-08-01
Series:mSphere
Assuntos:
Acinetobacter baumannii
LpxK
lipid A
outer membrane
Acceso en liña:https://journals.asm.org/doi/10.1128/mSphere.00199-17
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