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A New Test Statistic Based on Shrunken Sample Variance for Identifying Differentially Expressed Genes in Small Microarray Experiments

Choosing an appropriate statistic and precisely evaluating the false discovery rate (FDR) are both essential for devising an effective method for identifying differentially expressed genes in microarray data. The t -type score proposed by Pan et al. (2003) succeeded in suppressing false positives by...

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Päätekijät: Akihiro Hirakawa, Yasunori Sato, Chikuma Hamada, Isao Yoshimura
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publishing 2008-01-01
Sarja:Bioinformatics and Biology Insights
Linkit:https://doi.org/10.4137/BBI.S473
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