Miscibility and Solubility of Caffeine and Theophylline in Hydroxypropyl Methylcellulose
As amorphization may improve the solubility and bioavailability of a drug substance, the aim of this work was to assess to what extent the crystallinity of caffeine (CAF) and theophylline (TF) can be reduced by homogenization with a polymeric excipient. To realize this purpose, the physical mixtures...
Gardado en:
| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2021-11-01
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| Series: | Pharmaceutics |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/1999-4923/13/11/1836 |
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