The Cold-Adapted, Temperature-Sensitive SARS-CoV-2 Strain TS11 Is Attenuated in Syrian Hamsters and a Candidate Attenuated Vaccine

Live attenuated vaccines (LAVs) replicate in the respiratory/oral mucosa, mimic natural infection, and can induce mucosal and systemic immune responses to the full repertoire of SARS-CoV-2 structural/nonstructural proteins. Generally, LAVs produce broader and more durable protection than current COV...

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Detalhes bibliográficos

Principais autores:	Jiayu Xu, Mingde Liu, Xiaoyu Niu, Juliette Hanson, Kwonil Jung, Peng Ru, Huolin Tu, Daniel M. Jones, Anastasia N. Vlasova, Linda J. Saif, Qiuhong Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-12-01
coleção:	Viruses
Assuntos:	SARS-CoV-2 COVID-19 coronavirus vaccine cold-adaptation temperature-sensitive
Acesso em linha:	https://www.mdpi.com/1999-4915/15/1/95
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