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Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2

NIPBL is considered the cohesin loader. Here, the authors report that a drastic reduction of NIPBL levels reduces chromatin-bound cohesin-STAG2 genome wide while cohesin-STAG1 increases and can still be found at CTCF-bound sites but cannot form loops.

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Detaylı Bibliyografya
Asıl Yazarlar: Dácil Alonso-Gil, Ana Cuadrado, Daniel Giménez-Llorente, Miriam Rodríguez-Corsino, Ana Losada
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2023-03-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-023-36900-7
Etiketler: Etiketle
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