Role of vascular smooth muscle phenotypic transformation induced by histone modifications in the development of abdominal aortic aneurysms

Abstract Abdominal aortic aneurysm (AAA) is a progressive vascular disorder closely associated with the phenotypic transformation of vascular smooth muscle cells (VSMCs). Histone modifications—including acetylation, methylation, phosphorylation, lactylation, succinylation, ubiquitination, and small...

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Autors principals:	Zihao Chen, Yunping Sun, Peng Zhu, Le Zhang, Jian Yang, Jing Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-10-01
Col·lecció:	Clinical Epigenetics
Matèries:	Vascular smooth muscle cells Histone modifications Phenotypic transformation Abdominal aortic aneurysm Epigenetic therapy
Accés en línia:	https://doi.org/10.1186/s13148-025-01990-1
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