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Short-term regulation of murine colonic NBCe1-B (electrogenic Na+/HCO3(-) cotransporter) membrane expression and activity by protein kinase C.

The colonic mucosa actively secretes HCO3(-), and several lines of evidence point to an important role of Na+/HCO3(-) cotransport (NBC) as a basolateral HCO3(-) import pathway. We could recently demonstrate that the predominant NBC isoform in murine colonic crypts is electrogenic NBCe1-B, and that s...

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Autori principali: Oliver May, Haoyang Yu, Brigitte Riederer, Michael P Manns, Ursula Seidler, Oliver Bachmann
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3958514?pdf=render
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