Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria

Rationale: The association between non-tuberculous mycobacterial lung disease and alpha-1-antitrypsin (AAT) deficiency is likely due, in part, to underlying emphysema or bronchiectasis. But there is increasing evidence that AAT itself enhances host immunity against microbial pathogens and thus defic...

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Detalhes bibliográficos

Principais autores:	Xiyuan Bai, An Bai, Jennifer R. Honda, Charles Eichstaedt, Ariel Musheyev, Zhihong Feng, Gwen Huitt, Ronald Harbeck, Beata Kosmider, Robert A. Sandhaus, Edward D. Chan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-06-01
coleção:	Frontiers in Immunology
Assuntos:	autophagy mycobacteria nuclear factor-kappa B phagosome-lysosome fusion serine protease inhibitor
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01417/full
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