Salivary microbial signature highlighting actinomyces as a predictor of immune-checkpoint inhibitor monotherapy response in advanced non–small cell lung cancer

Abstract Background Immune checkpoint inhibitors (ICIs) have improved survival in advanced non-small cell lung cancer (NSCLC), yet reliable biomarkers beyond programmed death-ligand 1 (PD-L1) expression remain limited. Increasing evidence links the gut microbiome to ICI activity, but the predictive...

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Detalhes bibliográficos

Principais autores:	Silvia Cavaliere, Marta Fogolari, Michele Iuliani, Simone Foderaro, Alessio Cortellini, Sonia Simonetti, Emanuele Claudio Mingo, Silvia Calagna, Marco Russano, Bruno Vincenzi, Giuseppe Tonini, Silvia Angeletti, Francesco Pantano
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	Journal of Translational Medicine
Assuntos:	Salivary microbiome Immune-checkpoint inhibitors Non–small cell lung cancer Actinomyces
Acesso em linha:	https://doi.org/10.1186/s12967-025-07570-4
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