MIZ-1 controls transcriptional programs required for BCR signaling, actin dynamics, and naïve B cell survival

B cell receptor (BCR) signaling is required for the regulation of normal B lymphocyte development. However, many B cell lymphoma subtypes employ constitutive BCR signaling for transformation, survival, and growth. Here we report that mice expressing a POZ domain-deficient MIZ-1 (MIZ-1ΔPOZ), a well-k...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Julie Ross, Eva-Maria Piskor, Charles Joly-Beauparlant, Lucia Paola Gabrielli Tabarez, Elie El Ghorayeb, Arnaud Droit, Christian Kosan, Tarik Möröy
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-03-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	B cell activation B cell receptor Miz-1 signaling survival
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1758550/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!