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Virus detection by short read high throughput sequencing in a high virus low cellular background

Abstract The safety of all biological products includes demonstrating the absence of adventitious viruses by testing various types of samples at different stages of the manufacturing process. Seven laboratories evaluated short-read high-throughput sequencing (HTS) for sensitivity and breadth of adve...

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Hauptverfasser: Pei-Ju Chin, Christophe Lambert, Pascale Beurdelay, Robert L. Charlebois, Anne-Sophie Colinet, Marc Eloit, Shanaz Gilchrist, Maria Gilleece, Matthew Hess, Andreas Leimbach, Tom J. B. de Man, Olivier Vandeputte, Dawid Walas, Weihong Wang, Arifa S. Khan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-03-01
Schriftenreihe:npj Vaccines
Online-Zugang:https://doi.org/10.1038/s41541-025-01104-1
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