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Production of Recombinant Denileukin Diftitox: Assessment in the Lab-scale Bioreactor

Introduction: Denileukin diftitox is a recombinant immunotoxin composed of truncated diphtheria toxin fused to human interleukin 2 (DT389-IL2). It is a candidate for protein therapy of lymphoma. This work aims to investigate DT389-IL2 production using a recombinant strain of Escherichia coli in the...

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Bibliografiske detaljer
Principais autores: Seyed Morteza Robatjazi, Sanaz Mahboudi, Mehdi Zeinoddini
Format: Artigo
Sprog:Inglês
Udgivet: Mazandaran University of Medical Sciences and Health Services 2019-08-01
Serier:Research in Molecular Medicine
Fag:
Online adgang:http://rmm.mazums.ac.ir/article-1-328-en.html
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