Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of liquids in awake rats

CONTEXT: Methotrexate and other anticancer agents can induce intestinal mucositis, which is one of the most common limiting factor that prevent further dose escalation of the methotrexate. OBJECTIVES: To evaluate the gastric emptying and gastrointestinal transit of liquids in methotrexate-induced in...

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Главные авторы:	Pedro M. G. Soares, Lorena O. Lopes, José Maurício S. C. Mota, José Nelson Belarmino-Filho, Ronaldo A. Ribeiro, Marcellus Henrique L. P. de Souza
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE 2011-03-01
Серии:	Arquivos de Gastroenterologia
Предметы:	Mucosite Metotrexato Esvaziamento gástrico Trânsito gastrointestinal Ratos
Online-ссылка:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032011000100016&lng=en&tlng=en
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