Single-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis

Abstract Periodontitis affects billions of people worldwide. To address relationships of periodontal niche cell types and microbes in periodontitis, we generated an integrated single-cell RNA sequencing (scRNAseq) atlas of human periodontium (34-sample, 105918-cell), including sulcular and junctiona...

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Hlavní autoři:	Quinn T. Easter, Bruno Fernandes Matuck, Germán Beldorati Stark, Catherine L. Worth, Alexander V. Predeus, Brayon Fremin, Khoa Huynh, Vaishnavi Ranganathan, Zhi Ren, Diana Pereira, Brittany T. Rupp, Theresa Weaver, Kathryn Miller, Paola Perez, Akira Hasuike, Zhaoxu Chen, Mandy Bush, Xufeng Qu, Janice Lee, Scott H. Randell, Shannon M. Wallet, Inês Sequeira, Hyun Koo, Katarzyna M. Tyc, Jinze Liu, Kang I. Ko, Sarah A. Teichmann, Kevin M. Byrd
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-06-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-49037-y
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