Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience

AimSARS-CoV-2 infection is a world-wide public health problem. Several aspects of its pathogenesis and the related clinical consequences still need elucidation. In Italy, Sardinia has had very low numbers of infections. Taking advantage of the low genetic polymorphism in the Sardinian population, we...

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Principais autores:	Roberto Littera, Marcello Campagna, Silvia Deidda, Goffredo Angioni, Selene Cipri, Maurizio Melis, Davide Firinu, Simonetta Santus, Alberto Lai, Rita Porcella, Sara Lai, Stefania Rassu, Rosetta Scioscia, Federico Meloni, Daniele Schirru, William Cordeddu, Marta Anna Kowalik, Maria Serra, Paola Ragatzu, Mauro Giovanni Carta, Stefano Del Giacco, Angelo Restivo, Simona Deidda, Sandro Orrù, Antonella Palimodde, Roberto Perra, Germano Orrù, Maria Conti, Cinzia Balestrieri, Giancarlo Serra, Simona Onali, Francesco Marongiu, Andrea Perra, Luchino Chessa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-12-01
coleção:	Frontiers in Immunology
Assuntos:	human leukocyte antigen SARS-CoV-2 infection immunogenetic background COVID-19 severity Sardinian population alleles
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.605688/full
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