Genetic variants of AcrAB and OqxAB and the impact of efflux pump inhibition on ciprofloxacin and amikacin resistance in clinical isolates of Klebsiella pneumoniae from Lima, Peru

Abstract Background Klebsiella pneumoniae is a World Health Organization priority pathogen because of its rapidly accumulating resistance to multiple drug classes. Over-expression of the AcrAB and OqxAB Resistance-Nodulation-Division (RND) efflux pumps is a key mechanism, yet genomic data on these s...

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Principais autores:	Deysi Aguilar-Luis, Wilmer Silva-Caso, Giancarlo Pérez-Lazo, Liliana Morales-Castillo, Marta Camps, Fernando Soto-Febres, Miguel Angel Aguilar-Luis, Ronald Aquino-Ortega, Juana del Valle-Mendoza
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-03-01
Series:	BMC Microbiology
Assuntos:	Efflux pump Klebsiella pneumoniae Inhibitors of efflux pumps
Acceso en liña:	https://doi.org/10.1186/s12866-026-04847-6
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