daf-16/FOXO blocks adult cell fate in Caenorhabditis elegans dauer larvae via lin-41/TRIM71.

Many tissue-specific stem cells maintain the ability to produce multiple cell types during long periods of non-division, or quiescence. FOXO transcription factors promote quiescence and stem cell maintenance, but the mechanisms by which FOXO proteins promote multipotency during quiescence are still...

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Autores principales:	Matthew J Wirick, Allison R Cale, Isaac T Smith, Amelia F Alessi, Margaret R Starostik, Liberta Cuko, Kyal Lalk, Mikayla N Schmidt, Benjamin S Olson, Payton M Salomon, Alexis Santos, Axel Schmitter-Sánchez, Himani Galagali, Kevin J Ranke, Payton A Wolbert, Macy L Knoblock, John K Kim, Xantha Karp
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2021-11-01
Colección:	PLoS Genetics
Acceso en línea:	https://doi.org/10.1371/journal.pgen.1009881
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