Differential Effects of Alarmins on Human and Mouse Basophils

Epithelial-derived alarmins (IL-33, TSLP, and IL-25) play an upstream role in the pathogenesis of asthma. Basophil-derived cytokines are a pivotal component of allergic inflammation. We evaluated the in vitro effects of IL-33, TSLP, and IL-25, alone and in combination with IL-3 on purified periphera...

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Principais autores:	Adriana R. Gambardella, Remo Poto, Valentina Tirelli, John T. Schroeder, Gianni Marone, Fabrizio Mattei, Gilda Varricchi, Giovanna Schiavoni
格式:	Artigo
语言:	Inglês
出版:	Frontiers Media S.A. 2022-05-01
丛编:	Frontiers in Immunology
主题:	allergy asthma basophils IL-4 IL-13 IL-25
在线阅读:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.894163/full
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